Paget's disease of the breast or nipple
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Etiology
- associated with underlying ductal carcinoma of the breast
Pathology
- infiltration of the nipple epidermis by neoplastic cells
* histopathology images[3]
* electron microscopy images[3]
Clinical manifestations
- erythematous, scaling weeping eczematous eruption or ulceration on the nipple spreading to the areola
Diagnostic procedures
Differential diagnosis
- squamous cell carcinoma in situ[5]
- malignant melanoma
- atopic dermatitis: hisopathology shows spongiotic dermatitis pattern
- nipple candidiasis[5]
More general terms
Additional terms
References
- ↑ Mayo Internal Medicine Board Review, 1998-99, Prakash UBS (ed) Lippincott-Raven, Philadelphia, 1998, pg 170-71
- ↑ Medical Knowledge Self Assessment Program (MKSAP) 17, 18. American College of Physicians, Philadelphia 2015, 2018.
Medical Knowledge Self Assessment Program (MKSAP) 19 Board Basics. An Enhancement to MKSAP19. American College of Physicians, Philadelphia 2022 - ↑ 3.0 3.1 3.2 3.3 Elston CA, Elston DM (images) Medscape: Mammary Paget Disease http://emedicine.medscape.com/article/1101235-overview
- ↑ 4.0 4.1 DermNet NZ. Mammary Paget disease (images) http://www.dermnetnz.org/site-age-specific/paget.html
- ↑ 5.0 5.1 5.2 Zengin HB, Tan PH, Liu R, Smoller BR. 'Eczematous' dermatitis of the nipple: clinical and histopathological differential diagnosis of Paget disease. Pathology. 2024 Apr;56(3):300-312. PMID: https://pubmed.ncbi.nlm.nih.gov/38307774 Review.