apheresis
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Introduction
Removal of blood or one of its components from the body for clinical purposes, generally by automated blood cell separators.
Procedure
- cytapheresis removes cellular constituents
- plasmapheresis removes plasma returning cellular constituents
- photopheresis irradiates cellular constituents ex vivo
- selective LDL cholesterol removal for familial hypercholesterolemia[1]
Complications
- hypofibrinogenemia
- removal of plasma removes plasma proteins including fibrinogen[1]
Management
- stop ACE inhibitor 24 hours before elective apheresis[1]
More general terms
More specific terms
References
- ↑ 1.0 1.1 1.2 1.3 Medical Knowledge Self Assessment Program (MKSAP) 11, 16. American College of Physicians, Philadelphia 1998, 2012
Medical Knowledge Self Assessment Program (MKSAP) 20 American College of Physicians, Philadelphia 2025 - ↑ Okafor C, Ward DM, Mokrzycki MH et al Introduction and overview of therapeutic apheresis. J Clin Apher. 2010;25(5):240-9 PMID: https://pubmed.ncbi.nlm.nih.gov/20806281
- ↑ Szczepiorkowski ZM, Winters JL, Bandarenko N et al Guidelines on the use of therapeutic apheresis in clinical practice--evidence-based approach from the Apheresis Applications Committee of the American Society for Apheresis. J Clin Apher. 2010;25(3):83-177. PMID: https://pubmed.ncbi.nlm.nih.gov/20568098
- ↑ Padmanabhan A, Connelly-Smith L, Aqui N, et al. Guidelines on the use of therapeutic apheresis in clinical practice - evidence-based approach from the writing committee of the American Society for Apheresis: the eighth special issue. J Clin Apher. 2019;34:171-354. PMID: https://pubmed.ncbi.nlm.nih.gov/31180581