cancer antigen CA 72-4 in serum

Reference interval

• < 4 ng/mL

Increases

• presence in serum associated with:
  • adenocarcinomas of the gastrointestinal tract
    • elevated in 50% of patients gastric cancer
  • adenocarcinoma of the ovary
  • adenocarcinoma of the breast

Methods

• IRMA

Specimen

(specimen requirements)

• serum
• stable up to 24 hours at 2-8 degrees C
• for longer periods, store at -20 degrees C (avoid repetitive freeze-thaw cycles)

Procedure

• the test uses two antibodies
  • CC49 purified against highly purified TAG-72
  • B72-3 raised against a membrane fraction of a human breast cancer cell line

Notes

• antigen of mucin-type high molecular weight glycoprotein,
• tumor-associated glycoprotein 72 (TAG-72).

More general terms

• cancer antigen CA 72-4 in body fluid

Additional terms

• breast; mammary gland
• gastric cancer
• malignant neoplasm (cancer)
• ovarian cancer
• tumor-associated glycoprotein 72 (TAG-72)