trichloroethylene
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Introduction
-..........-
Cl Cl
/
=
/
H Cl
Characteristics
- clear non-flammable liquid with a sweet smell
Uses
- commonly used as an industrial solvent
- found in common consumer & manufacturing products
- degreasing agents, furniture care, auto repair products
- was used as a general inhalation anesthetic, use abandon in 1980s
- Environmental Protection Agency has bannedd use of trichloroethylene Dec 2024
Epidemiology
- ground water contamination
Adverse effects
- cardiac arrhythmias
- neurologic dysfunction in combination with alkali used for carbon dioxide absorbtion when used with soda lime
- hepatotoxicity, liver cancer
- nephrotoxic, kidney cancer
- non-Hodgkin's lymphoma
- exposure associated with risk of Parkinson's disease[2][3]
More general terms
References
- ↑ Wikipedia: Trichloroethylene http://en.wikipedia.org/wiki/Trichloroethylene
- ↑ 2.0 2.1 Dorsey ER, Zafar M, Lettenberger SE et al Trichloroethylene: An Invisible Cause of Parkinson's Disease? Journal of Parkinson's Disease. 2023 13(2):203-218. March 14 PMID: https://pubmed.ncbi.nlm.nih.gov/36938742 https://content.iospress.com/articles/journal-of-parkinsons-disease/jpd225047
- ↑ 3.0 3.1 Krzyzanowski B, Beyene KM, Turner JR, Racette BA. Ambient Trichloroethylene Exposure and Parkinson Disease Risk in Medicare Beneficiaries. Neurology. 2025 Oct 21;105(8):e214174. PMID: https://pubmed.ncbi.nlm.nih.gov/41032742 PMCID: PMC12488192 Free PMC article