lipodermatosclerosis
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Etiology
Pathology
- capillary proliferation
- fat necrosis
- fibrosis of cutaneous & subcutaneous tissues
Clinical manifestations
- skin becomes reddish or brown because of hemosiderin deposition
- induration from fibrosis -> non-pitting, indurated skin
- painful, red-brown, atrophic nodules of adipose tissue
- indurated hyperpigmentation, may appear 'woody' in appearance & to palpation
- erythema is present[2]
- telangiectasias, varicosities, venous ulcers, & atrophie blanche may be present[2]
- frequently bilateral[2]
- legs may have an inverted bottle shape
Differential diagnosis
- stasis dermatitis
- pitting edema favors stasis dermatitis over lipodermatosclerosis, especially in the absence of significant induration or fibrosis [6-9]
Management
- for localized masses, (i.e. abdomen, thighs, upper arms) surgical resection has met some success
More general terms
References
- ↑ Brown KE eMedicine: Chronic venous insufficiency http://emedicine.medscape.com/article/461449-overview
- ↑ 2.0 2.1 2.2 2.3 Medical Knowledge Self Assessment Program (MKSAP) 15, 18. American College of Physicians, Philadelphia 2009, 2018.
Medical Knowledge Self Assessment Program (MKSAP) 20 American College of Physicians, Philadelphia 2025 - ↑ 3.0 3.1 DermNet NZ. Lipodermatosclerosis (images) http://www.dermnetnz.org/vascular/lipodermatosclerosis.html
- ↑ 4.0 4.1 Rashid RM, Barros BS (image) Hidden Heart Disease: 19 Dermatologic Clues You Should Know. Medscape. June 13, 2017. http://reference.medscape.com/slideshow/hidden-heart-disease-6004452
- ↑ Geriatric Review Syllabus, 11th edition (GRS11) Harper GM, Lyons WL, Potter JF (eds) American Geriatrics Society, 2022
- ↑ Bruce AJ, Bennett DD, Lohse CM, Rooke TW, Davis MD. Lipodermatosclerosis: review of cases evaluated at Mayo Clinic. J Am Acad Dermatol. 2002 Feb;46(2):187-92. PMID: https://pubmed.ncbi.nlm.nih.gov/11807428
- ↑ Choonhakarn C, Chaowattanapanit S, Julanon N. Lipodermatosclerosis: a clinicopathologic correlation. Int J Dermatol. 2016 Mar;55(3):303-8. PMID: https://pubmed.ncbi.nlm.nih.gov/26275890
- ↑ Walsh SN, Santa Cruz DJ. Lipodermatosclerosis: a clinicopathological study of 25 cases. J Am Acad Dermatol. 2010 Jun;62(6):1005-12. PMID: https://pubmed.ncbi.nlm.nih.gov/20466175
- ↑ 9.0 9.1 Vivas A, Lev-Tov H, Kirsner RS. Venous Leg Ulcers. Ann Intern Med. 2016 Aug 2;165(3):ITC17-ITC32. PMID: https://pubmed.ncbi.nlm.nih.gov/27479227 Review https://www.acpjournals.org/doi/10.7326/AITC201608020