spontaneous breathing trial (SBT)

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Introduction

also see ventilation weaning

Indications

Clinical significance

Procedure

* no difference between 2 methods in reintubation or ventilator-free days[4]

* pressure support & more frequent trials increases time to success[5]

* a daily trial without pressure support recommended[5]

Management

More general terms

Additional terms

References

  1. 1.0 1.1 1.2 Medical Knowledge Self Assessment Program (MKSAP) 17, 18, 19. American College of Physicians, Philadelphia 2015, 2018, 2022.
    Medical Knowledge Self Assessment Program (MKSAP) 20 American College of Physicians, Philadelphia 2025
  2. Loinc
  3. 3.0 3.1 Subira C, Hernandez G, Vazquez A et al. Effect of pressure support vs T-piece ventilation strategies during spontaneous breathing trials on successful extubation among patients receiving mechanical ventilation: A randomized clinical trial. JAMA 2019 Jun 11; 321:2175. PMID: https://pubmed.ncbi.nlm.nih.gov/31184740 https://jamanetwork.com/journals/jama/fullarticle/2735502
    Girard TD, Burns KEA. Revisiting, reframing, and casting a new light on liberation from mechanical ventilation. JAMA 2019 Jun 11; 321:2167. PMID: https://pubmed.ncbi.nlm.nih.gov/31184723 https://jamanetwork.com/journals/jama/fullarticle/2735481
  4. 4.0 4.1 4.2 Thille AW et al. Spontaneous-breathing trials with pressure-support ventilation or a T-piece. N Engl J Med 2022 Nov 17; 387:1843-1854. PMID: https://pubmed.ncbi.nlm.nih.gov/36286317 https://www.nejm.org/doi/10.1056/NEJMoa2209041
  5. 5.0 5.1 5.2 Ippolito M, Sardo S, Tripodi VF et al. Association between spontaneous breathing trial methods and reintubation in adult critically ill patients: A systematic review and network meta-analysis of randomized controlled trials. Chest 2024 Nov 15; 166:1020. PMID: https://pubmed.ncbi.nlm.nih.gov/38964674 https://journal.chestnet.org/article/S0012-3692(24)04575-6/abstract
    Burns KEA, Wong J, Rizvi L et al. Frequency of screening and spontaneous breathing trial techniques: A randomized clinical trial. JAMA 2024 Dec 3; 332:1808-2021 PMID: https://pubmed.ncbi.nlm.nih.gov/39382222 Clinical Trial. https://jamanetwork.com/journals/jama/fullarticle/2824928