PfSEA-1 protein
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Pathology
- Plasmodium falciparum schizont egress antigen-1 (PfSEA-1)
- 244 KD parasite antigen expressed in schizont-infected erythrocytes
- role in parasite replication by promoting schizont rupture[1]
- antibodies to PfSEA-1 may confer immunity to malaria
Pharmacology
- potential target for malaria vaccine[1]
References
- ↑ 1.0 1.1 1.2 Raj DK et al. Antibodies to PfSEA-1 block parasite egress from RBCs and protect against malaria infection. Science 2014 May 23; 344:871 PMID: https://pubmed.ncbi.nlm.nih.gov/24855263