cancer of unknown primary

^[1]^[2]^[3]

Radiology

special cases:

carcinoma identified in isolated enlarged inguinal lymph node
- if CT negative
  - examination of the vulva, vagina, cervix, anus (women)*
  - penis, anus (men)*
axillary presentation of adenocarcinoma
- axillary dissection & treat as primary breast cancer^[1]

↑ ^1.0 ^1.1 Medical Knowledge Self Assessment Program (MKSAP) 18, American College of Physicians, Philadelphia 2018
Medical Knowledge Self Assessment Program (MKSAP) 20 American College of Physicians, Philadelphia 2025
↑ Laprovitera N, Riefolo M, Ambrosini E, et al. Cancer of unknown primary: challenges and progress in clinical management. Cancers (Basel). Published online January 25, 2021. 2021;13(3):451. PMID: https://pubmed.ncbi.nlm.nih.gov/33504059
↑ NCCN Clinical Guidelines in Oncology. Occult Primary. Version 2.2024. https://www.nccn.org/professionals/physician_gls/pdf/occult.pdf