eosinophilic gastritis

Etiology

• idiopathic, possibly allergic
• generally occurs in atopic persons (suggested by eosinophilia)

Epidemiology

rare

Pathology

• infiltration of eosinophils into the stomach
• small intestine may be involved

Diagnostic procedures

• upper GI endoscopy
  • gastric mucosa may appear normal
  • gastric biology
    • eosinophils in gastric mucosa > 10/HPF
• allergy testing to identify foods to eliminate

Differential diagnosis

• drugs
  • parasitic infections
    • bacterial infections
• inflammatory bowel disease
  • Crohn's disease
• vasculitis
  • polyarteritis
  • allergic vasculitis
• hypereosinophilic syndrome
• connective tissue disease
  • scleroderma
• myeloproliferative disorders

Management

• food elimination (see eosinophilic esophagitis)
• glucocorticoids vs elemental diet if food elimination fails

More general terms

• gastritis