levocetirizine (Xyzal)
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Introduction
Tradename: Xyzal (Low-sedating antihistamine) 2.5-5 mg PO QD
Tabs: 2.5, 5 mg
Pharmacokinetics
- onset of action: 1 hour
elimination via liver
elimination via kidney
Adverse effects
- risk of pruritus after stopping long-term use of cetirizine or levocetirizine[3]
Mechanism of action
L-isomer of cetirizine
More general terms
References
- ↑ Prescriber's Letter 14(9): 2007 New drug: Xyzal (levocetirizine) Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=230910&pb=PRL (subscription needed) http://www.prescribersletter.com
- ↑ Prescriber's Letter 15(7): 2008 Comparison of Antihistamines Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=240707&pb=PRL (subscription needed) http://www.prescribersletter.com
- ↑ 3.0 3.1 Derman C FDA Warns About Rare, Severe Itching After Stopping Cetirizine or Levocetirizine. HCPLive May 20, 2025 https://www.hcplive.com/view/fda-warns-about-rare-severe-itching-after-stopping-cetirizine-or-levocetirizine
FDA. May 16, 2025 FDA requires warning about rare but severe itching after stopping long-term use of oral allergy medicines cetirizine or levocetirizine (Zyrtec, Xyzal, and other trade names https://www.fda.gov/drugs/drug-safety-and-availability/fda-requires-warning-about-rare-severe-itching-after-stopping-long-term-use-oral-allergy-medicines