cetirizine (Zyrtec, Alertisin, Reactine, Zerviate)
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Introduction
Tradename: Zyrtec, Reactine in Canada (low-sedating antihistamine) over-the-counter in 2008 (pending) 1/08[2]
Dosage
Tabs: 5, 10 mg
Syrup: 5 mg/5mL Ophthalmic 0.24% (Zerviate): 1 drop OU BID[4]
Pharmacokinetics
- onset of action: 1 hour
elimination via liver
elimination via kidney
Adverse effects
- risk of pruritus after stopping long-term use of cetirizine or levocetirizine[3][5]
Mechanism of action
More general terms
More specific terms
Component of
References
- ↑ The Pharmacological Basis of Therapeutics, 9th ed. Gilman et al, eds. Permagon Press/McGraw Hill, 1996
- ↑ 2.0 2.1 Prescriber's Letter 15(1): 2008 FDA Approves Zyrtec / Zyrtec-D for Over-the-counter (OTC) Use Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=240110&pb=PRL (subscription needed) http://www.prescribersletter.com
- ↑ 3.0 3.1 Prescriber's Letter 15(7): 2008 Comparison of Antihistamines Detail-Document#: http://prescribersletter.com/(5bhgn1a4ni4cyp2tvybwfh55)/pl/ArticleDD.aspx?li=1&st=1&cs=&s=PRL&pt=3&fpt=25&dd=240707&pb=PRL (subscription needed) http://www.prescribersletter.com
- ↑ 4.0 4.1 Brooks M. FDA Clears Cetirizine Eye Drops for Allergic Conjunctivitis, Medscape - Jun 01, 2017 http://www.medscape.com/viewarticle/880989
- ↑ 5.0 5.1 Derman C FDA Warns About Rare, Severe Itching After Stopping Cetirizine or Levocetirizine. HCPLive May 20, 2025 https://www.hcplive.com/view/fda-warns-about-rare-severe-itching-after-stopping-cetirizine-or-levocetirizine
FDA. May 16, 2025 FDA requires warning about rare but severe itching after stopping long-term use of oral allergy medicines cetirizine or levocetirizine (Zyrtec, Xyzal, and other trade names https://www.fda.gov/drugs/drug-safety-and-availability/fda-requires-warning-about-rare-severe-itching-after-stopping-long-term-use-oral-allergy-medicines