NADH (reduced nicotinamide adenine dinucleotide)
Jump to navigation
Jump to search
Comparative biology
- in aging mice, higher levels of hippocampal FTL1* results in reduces neuronal connectivity & memory decline
- reducing hippocampal levels of FTL1 in old mice with NADH supplementation# enhances neural connectivity & improves performance on memory tests
* FTL1 is a mouse-specific ferritin light chain
# supplementation with NAD+ described in humans does not seem to have anti-aging effect (see NAD)
More general terms
Additional terms
References
- ↑ Remesal L et al for the University of California - San Francisco Scientists found a protein that drives brain aging - and how to stop it. Science News. April 5, 2026 https://www.sciencedaily.com/releases/2026/04/260405065236.htm
Remesal L, Sucharov-Costa J, Wu Y et al Targeting iron-associated protein Ftl1 in the brain of old mice improves age-related cognitive impairment. Nat Aging. 2025 Oct;5(10):1957-1969. PMID: https://pubmed.ncbi.nlm.nih.gov/40830655 PMCID: PMC12532579 Free PMC article. https://www.nature.com/articles/s43587-025-00940-z